Home » Blog » The 5 Best Nicotinamide Riboside Supplement Brands (2023)
the 5 best nicotinamide riboside supplement brands

The 5 Best Nicotinamide Riboside Supplement Brands (2023)

In the ongoing quest for better health, Nicotinamide Riboside (NR) supplements have emerged as one of the go-to options for supporting longevity and well-being. These supplements play a vital role in increasing NAD+ levels, which is essential for maintaining cellular energy and combating aging. Below, we’ll dive into five of the best NR supplement brands and explore what sets them apart.

1. Renue by Science

Company Overview

Renue by Science aims to provide top-quality bioavailable longevity products at affordable prices. Founded by Bryan Nettles, the company focuses on nutrition, science, research, and healthy aging. With Chief Medical Advisor Dr. Clark Driggers, Renue by Science is a leader in wellness and anti-aging treatments.


The company’s core values include:

  • Moving the Science Forward
  • Driving the Price Down
  • Quality Assurance
  • Customer Service

Product: LIPO NR – Nicotinamide Riboside

  • Price: $74.95 (or subscribe and save 5%)
  • Dosage: 300 mg per capsule, 1 capsule serving size
  • Special Feature: Liposomal Delivery of NR ensures targeted and complete absorption, significantly improving bioavailability.

Renue by Science has proven its dedication to quality through meticulous 3rd party testing and a guaranteed 100% customer satisfaction policy. Their focus on liposomal delivery sets them apart, allowing for more effective supplementation Study 1, Study 2.

2. Tru Niagen

Company Overview

Tru Niagen stands out as one of the most researched and patented supplements on the market. With accolades from Nobel Prize winners and a plethora of global research collaborations, the company has firmly established itself as a pioneer in the field of health and wellness.

Product: Tru Niagen 300mg

  • Price: $119.95 (or subscribe & save for $105.00)
  • Dosage: 300mg per capsule, customizable dosage
  • Special Feature: One of the most well-researched NR supplements, backed by 2 Nobel Prize Winners, 40+ patents, 300+ published scientific studies.

Tru Niagen focuses on supporting healthy aging, brain function, heart health, and more. Their dedication to research and innovation shines through, offering a versatile serving size that can increase NAD+ levels by up to 51% in as little as two weeks.

3. Nootropics Depot

Company Overview

When it comes to quality and trust, Nootropics Depot stands out with their in-house analytical laboratory. Their commitment to quality is backed by a Fully ISO/IE 17025:2017 Accredited laboratory and 18 Full-Time Laboratory Scientists & Quality Control Personnel.

They’ve partnered with 11 Third-Party Laboratory Partners, and their participation in various international and national bodies like AOAC International and NIST ensures top-notch quality and standardization.

Nootropics Depot has taken great strides to redefine the analytical testing standards for the entire nootropic and supplement industry. Their transparency, resolve, and determination are evident in the state-of-the-art technology they employ and the quality products they offer.

Whether you’re a loyal or new customer, when you purchase a Nootropics Depot product, you can rest easy knowing that you’ll receive quality each and every time.

Product: Nicotinamide Riboside Capsules | 300mg | NAD+ Precursor

  • Price: $34.99 for
  • Dosage: Choose from 30ct., 90ct., or 365ct. 300mg bottles

As we age, our energy levels and vitality often decrease, and that’s where nicotinamide riboside (NR) comes into play. This naturally occurring Vitamin B3 derivative is a powerful NAD+ precursor, aiding in the rejuvenation of cellular energy.

4. Thorne Supplements

Company Overview

Thorne Supplements, experts in the field of human health, are committed to extending the health span of individuals through personalized, scientific wellness. With offerings that include personalized testing, educational resources, and products, Thorne aims to redefine what it means to live healthier for longer. Their promise is to bring your health to new heights.

Product: NiaCel 400

  • Price: $68/60 Capsules Dosage: Take 1 capsule one to two times daily, or as recommended by your healthcare practitioner.
  • Dosage: 415mg NR

NiaCel 400 focuses on supporting youthful vitality through the exclusive form of NR, increasing the coenzyme NAD+. Lack of sleep, poor diet, stress, and the natural aging process can deplete NAD+, leading to symptoms of early aging and reduced vitality. Thorne’s NiaCel 400 aims to make age feel like just a number by boosting NAD+ levels, supporting everything from exercise efficiency and vibrant energy to a normal sleep-wake cycle.

What sets Thorne apart is their ambition to empower individuals to live healthier for longer through personalized solutions, believing in the idea that scientific wellness can create happier and healthier lives. You can find more about Thorne’s approach to wellness here, and detailed insights into NiaCel 400’s benefits can be found at this product page.

5. Life Extension

Company Overview

Life Extension has earned a reputation for meticulously researching the latest anti-aging advancements and turning them into top-quality supplements. With a commitment to quality, transparency, and product innovation, Life Extension has set a benchmark in the health and wellness industry.

  • Product: NAD+ Cell Regenerator™
  • Price: $18.00
  • Dosage: 100mg per capsule, 30 vegetarian capsules
  • Special Feature: Contains 100 mg of NIAGEN®, the first commercially available form of nicotinamide riboside. Clinically studied, this patented compound helps maintain youthful levels of NAD+, promoting healthy cellular metabolism and fighting general fatigue at the cellular level.

Life Extension’s NAD+ Cell Regenerator™ aims to rejuvenate your energy levels by boosting the cellular coenzyme NAD+, necessary for ATP production. The NIAGEN® nicotinamide riboside in the supplement has been proven to increase NAD+ levels by 40% in just 30 days, contributing to healthy aging and supporting cognitive functions.

With over 40 years of experience, Life Extension continues to prioritize the needs of its customers. Their focus on product transparency, sustainability, and high-quality formulations earned them a 98% recommendation rate from their clientele. They also provide resources like access to doctors, nutritionists, nurses, and blood testing services, all dedicated to empowering individuals to live a healthier life.

Life Extension’s NAD+ Cell Regenerator™ stands as a testament to their dedication to wellness. Its benefits extend to supporting longevity, youthful energy, and metabolic health, making it a powerful addition to anyone’s daily wellness routine.


In a world increasingly filled with synthetic solutions and quick-fixes, the quest for natural and effective anti-aging and wellness solutions is ever-growing. The brands listed above stand out as leading pioneers in the health industry, offering top-quality Nicotinamide Riboside (NR) supplements. Their commitment to scientific rigor, innovative approaches, customer satisfaction, and affordability sets them apart in an industry flooded with mediocrity.

  1. Renue by Science‘s dedication to liposomal delivery and their mission of making science-forward products accessible to all ensures a bright future in healthy aging.
  2. Tru Niagen takes its place as a vanguard of wellness through continuous research and innovation, emphasizing a holistic approach to health.
  3. Nootropics Depot promises quality and trust with their commitment to analytical testing standards, embodying the spirit of integrity and transparency in the supplement industry.
  4. Thorne Supplements is on a path to redefine healthy living through scientific wellness, focusing on personalized solutions that meet individual needs.
  5. Life Extension echoes the essence of dedication to wellness through quality formulations and extensive resources, turning anti-aging advancements into practical, daily supplements.

Whether you’re seeking to boost energy levels, rejuvenate cellular functions, or simply maintain a vibrant lifestyle, these brands offer not just products, but a comprehensive approach to well-being. From the clinically studied compound NIAGEN® in Life Extension’s NAD+ Cell Regenerator™ to the unique offering of NiaCel 400 by Thorne, the solutions are diverse but united by a common purpose: promoting healthy living and aging.

Selecting the right NR supplement isn’t just about price or popularity. It’s about aligning with the brand that resonates with your values and needs. It’s about taking control of your health and making choices that elevate you to a better life. You can find more about the science behind NR and its connection to NAD+ in this insightful study by Cell Metabolism and explore a review on the effects of Nicotinamide Riboside on aging at Nature Communications.

Remember, wellness is not a destination but a journey. And in that journey, NR supplements may just be the fuel your body needs to conquer new horizons, transforming what was once considered an inevitable decline into an adventure filled with vitality and vigor.


  1. Link to Study 1 – An in-depth look into liposomal delivery and its impact on bioavailability.
  2. Link to Study 2 – Research on the effectiveness of NR capsules and how they affect NAD+ levels.

Leave a Comment

Your email address will not be published. Required fields are marked *

Shopping Cart
%d bloggers like this: