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tru niagen vs nmn

Tru Niagen vs. NMN: A Comprehensive Comparison

In the wellness community, the conversation about boosting NAD+ levels for cellular health is gaining momentum. Two buzzworthy supplements leading this conversation are Tru Niagen and NMN (Nicotinamide Mononucleotide). But what’s the difference between these two? Let’s deep dive into Tru Niagen vs. NMN to uncover the details, from science to pricing.

Understanding NAD+

Firstly, let’s understand why NAD+ is so crucial. NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme found in all living cells. It plays a significant role in cellular metabolism and is essential for life as we know it. Unfortunately, our NAD+ levels decline with age and stress, contributing to various health issues, such as reduced energy levels and faster aging.

The Benefits of Elevated NAD+ Levels in the Human Body

When it comes to anti-aging and cellular repair, one molecule stands out: Nicotinamide adenine dinucleotide (NAD+). It’s a crucial element for many cellular processes, such as metabolism and DNA repair. But as we age, NAD+ levels naturally decline, leading to cellular dysfunction and increased susceptibility to diseases. This is where NMN (Nicotinamide Mononucleotide) comes into the picture. Elevating NAD+ levels can have a profound impact on how your body functions, from cellular activity to overall health and wellness. Here’s why it matters:

Boosts Cellular Energy Production:

The molecule NAD+ helps convert food into energy within the mitochondria, the “powerhouse” of the cell. Higher NMN levels can thus elevate NAD+ levels, improving the efficiency of energy production in cells. This could potentially lead to increased vitality and less overall fatigue.

Enhanced Cognitive Function:

Our brains are highly energy-dependent, and they suffer when NAD+ levels dip. By boosting NMN, which in turn raises NAD+ levels, cognitive functions such as focus, memory, and problem-solving can be significantly improved. This is especially critical for aging populations, where cognitive decline becomes a concern.

DNA Repair and Cellular Health:

NAD+ plays a vital role in activating proteins that repair damaged DNA. This is incredibly important because DNA damage can lead to cancer and other age-related diseases. By elevating NMN levels, you’re essentially aiding your body’s own natural repair mechanisms.

Anti-Inflammatory Effects:

Recent studies have shown that increasing NA+ levels can reduce inflammation at the cellular level. Inflammation is a precursor to numerous diseases, including cardiovascular diseases and autoimmune disorders. Therefore, a boost in NAD+ could be instrumental in preventing a plethora of health issues.

Improved Metabolic Functions:

Elevated NAD+ levels have also been linked to improved insulin sensitivity, reduced cholesterol levels, and a healthier body weight. All these factors contribute to a better metabolic profile, reducing the risk of diseases like type 2 diabetes.

Heart Health:

NAD+ can improve the overall health of your cardiovascular system. It has been linked to improving blood flow and cardiac function, thereby potentially reducing the risk of heart-related conditions.

Aids in Longevity:

Though still a budding area of research, there’s promising evidence to suggest that elevated NAD+ levels can extend lifespan. This is primarily due to its effects on sirtuin activation, a class of proteins that have been associated with aging and longevity.

Incorporating NMN into your wellness regimen could offer a multi-targeted approach to aging and disease prevention. It’s an exciting frontier in the world of health science, one that could reshape our understanding of aging and how we approach longevity and wellness.

Note: Before supplementing with NMN, it’s always wise to consult with a healthcare provider, especially if you’re currently managing any health conditions or are pregnant or breastfeeding.

By diving deeper into the benefits of elevated NAD+ levels, you’re not just skimming the surface of health; you’re delving into a world that could very well be the future of preventative healthcare.

What is Tru Niagen?

Tru Niagen is a supplement that aims to boost NAD+ levels. Its active ingredient is Niagen, a patented form of Nicotinamide Riboside (NR), which is a precursor to NAD+. It’s vegetarian-friendly, FDA-notified as GRAS, and NSF for Sport® certified. A single capsule (300mg) can purportedly boost your NAD+ levels by up to 51% in as little as two weeks.


  • Clinically proven to increase NAD+ levels.
  • FDA-notified as Generally Recognized as Safe (GRAS).
  • Broad international approval for sale.


  • Price can range from $47 to $229.95, depending on the quantity.
  • Capsule form might not be as bioavailable as other delivery methods.

NMN Renue By Science coupon code

What is NMN?

Nicotinamide Mononucleotide (NMN) is another NAD+ precursor. The specific product we’re looking at is Renue By Science’s Fast Dissolve NMN Powder. Designed for sublingual (under the tongue) use, it offers superior bioavailability compared to capsules.


  • High bioavailability, especially through sublingual use.
  • Powder form allows for portability and varying dosage.
  • Faster acting, noticeable effects in minutes.


  • Less clinical backing compared to Tru Niagen.
  • Costs $99.05 for 100 grams, which may not be budget-friendly for all users.

Science-Backed Claims

Tru Niagen claims its product is clinically proven to boost NAD+ levels. Multiple human clinical studies back this, demonstrating increased NAD+ levels by up to 50% in just two weeks of regular 300mg/day supplementation 1.

NMN, although with promising results in animal studies 2, has limited human clinical trials. However, it’s interesting to note that sublingual delivery is suggested to be even more bioavailable than intraperitoneal injection, based on studies of other substances 3.


Tru Niagen can cost you anywhere between $47 to $229.95 depending on the quantity. On the other hand, Renue by Science’s NMN powder costs $99.05 for 100 grams. While both aren’t exactly cheap, if you’re looking for cost-effectiveness coupled with high bioavailability, NMN seems to have a slight edge.


Let’s be honest; nobody enjoys the wrinkles, lower energy, and the general toll aging takes on our bodies. While aging is a natural process, what if we could slow it down, even just a bit? What if we could not only add years to our lives but also life to our years? The answer might just be coursing through our veins and living in our cells right now: NMN.

The scientific community is buzzing about the potential of NMN and for good reason. From supercharging cellular energy production to paving the way for DNA repair, this molecule is like the Swiss Army knife of wellness. Sure, it’s not a magical “cure-all,” but its multi-faceted benefits offer a holistic approach to health. You’re not just boosting your energy; you’re fortifying your cellular army, sharpening your mental acumen, and maybe, just maybe, unlocking the secret to a longer, healthier life.

As research continues, we might discover even more benefits of elevated NMN levels. But for now, it’s safe to say that this small molecule packs a hefty punch in the wellness arena. So, if you’re not just looking for another supplement but a promising avenue towards holistic well-being, then it’s time to turn your attention to NMN. After all, the future of wellness isn’t just about treating symptoms; it’s about understanding and nourishing our bodies at their most fundamental level. And that journey, my friends, starts with a single molecule.


  1. Nicotinamide riboside is uniquely and orally bioavailable in mice and humans
  2. A conserved NAD+ binding pocket that regulates protein-protein interactions during aging
  3. Sublingual and buccal drug delivery

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