can you take magnesium glycinate and magnesium l-threonate together

Can You Take Magnesium Glycinate and Magnesium L-Threonate Together? A Comprehensive Guide

Magnesium is a vital mineral that plays a crucial role in many bodily functions. From the synthesis of DNA to muscle contraction, magnesium s indeed indispensable. But with so many forms available, a question arises: Can you take magnesium glycinate and magnesium l-threonate together?

Yes, you can take magnesium glycinate and magnesium l-threonate together. By understanding their unique properties and potential synergies, users can benefit from both calming and cognitive enhancement effects.

Magnesium Glycinate: What It Is and Why It’s Important

Magnesium glycinate is a form of magnesium that’s chelated to glycine, an amino acid that helps increase absorption. This form of magnesium is known for its calming effects and is often recommended for improving sleep quality and reducing anxiety.

Magnesium L-Threonate: A Unique Form for Cognitive Enhancement

Magnesium L-Threonate, also known as Magtein, has become increasingly popular due to its ability to cross the blood-brain barrier. Its cognitive-enhancing properties make it an exciting topic, particularly in the realm of biohacking and treating conditions like ADHD.

It is also considered one of the best forms of magnesium for kids when taken under the guidance of a medical professional.

Can You Take Them Together?

Combining magnesium glycinate and magnesium l-threonate seems like an appealing idea, considering their distinct benefits. One caters to mental well-being, while the other is celebrated for cognitive prowess. But can you take them together?

Live Momentous coupon code (1)

Potential Benefits

  1. Enhanced Absorption: Both magnesium glycinate and magnesium l-threonate are highly bioavailable, meaning they are more readily absorbed by the body.
  2. Complementary Functions: While magnesium glycinate provides calming effects, magnesium l-threonate may enhance cognitive function, thus supporting both mind and body.
  3. Inclusion in Nootropic and Biohacking Protocols: Both these forms are listed among the best nootropics for ADHD and biohacking, indicating their versatile uses.

Precautions and Considerations

  1. Dosage Management: Overconsumption of magnesium may lead to gastrointestinal issues. Thus, it’s essential to consult with a healthcare provider to determine the right dosage.
  2. Individual Needs and Health Conditions: Each person’s need for magnesium varies, and underlying health conditions may influence the decision to combine these supplements.
  3. Stopping use: While you won’t experience withdrawal side effects, you might notice a decline in cognitive boosting, anxiety, or restlessness at night upon stopping its use.

Exploring the Synergistic Effects

Combining magnesium glycinate with magnesium l-threonate may offer synergistic effects, further enhancing their individual benefits.

Anxiety and Stress Reduction

Magnesium glycinate’s calming properties can be a boon for those battling anxiety or stress. When paired with magnesium l-threonate’s brain-enhancing effects, it can form a powerful duo to combat the modern stresses of life. More research is required to establish this connection, but the initial understanding is promising.

Improved Sleep Quality

Magnesium is linked to the regulation of neurotransmitters that help induce sleep. The combination of magnesium glycinate and magnesium l-threonate might lead to improved sleep quality by working on different levels of the sleep mechanism. Studies that specifically explore this combination could provide more insights.

Cognitive Function and Mental Clarity

Magnesium l-threonate’s cognitive-boosting effects are well documented in studies like Slutsky, I., et al. (2010). Combining it with magnesium glycinate might improve mental clarity, focus, and overall cognitive function.

Related: 7 best Magnesium L-Threronate brands

7 best magnesium l-threonate supplement brands

Best Practices for Combining Magnesium Glycinate and Magnesium L-Threonate

Start with Professional Guidance

Always consult with a healthcare provider to understand your unique needs and how these two forms of magnesium may benefit you.

Monitor Your Response

Since these supplements work on different aspects of well-being, monitoring your response and adjusting the dosage as needed is crucial.

Quality Matters

Choosing high-quality supplements from reputable brands can make a difference in efficacy. Here’s a guide to the 7 best Magnesium L-Threronate brands to help you make an informed decision.

A Holistic Approach to Health and Wellness

The combined use of magnesium glycinate and magnesium l-threonate aligns well with the holistic approach to health and wellness. Their individual and combined effects can be part of a broader strategy to achieve mental calmness and cognitive enhancement.

Part of a Balanced Diet

Remember, supplements are just that – supplemental. A balanced diet rich in magnesium-containing foods should always be the foundation.

Lifestyle Considerations

Incorporating practices like mindfulness, meditation, and exercise can further amplify the benefits of these supplements.

Conclusion and Final Thoughts

As with any supplementation, professional guidance is strongly encouraged. Those interested in learning more about magnesium l-threonate brands can explore this comprehensive guide on the 7 best Magnesium L-Threronate brands.

Combining magnesium glycinate with magnesium l-threonate can be a thoughtful strategy for those seeking a multifaceted approach to mental well-being and cognitive enhancement. Understanding their unique properties, potential synergies, and precautions ensures safe and effective use.

The exploration of their combination is an exciting development in the fields of nootropics and biohacking, aligning with a holistic approach to wellness.


  1. Slutsky, I., et al. (2010). Enhancement of learning and memory by elevating brain magnesium. Neuron, 65(2), 165-177.
  2. Coudray, C., et al. (2005). Study of magnesium bioavailability from ten organic and inorganic Mg salts in Mg-depleted rats using a stable isotope approach. Magnesium Research, 18(4), 215-223.
Shopping Cart